The European Society of Cardiology has published updated clinical guidelines for the management of infarction in patients with elevated ST segments (STEMI). They cover everything from epidemiology, emergency care, reperfusion therapy, hospitalization, long-term therapies and potential complications to assessment protocols and suggestions for future research. Among the key messages, the text noted that while the mortality rate for ischemic heart disease is decreasing, it remains the most common cause of death globally. It also stressed the need for equal gender treatment, while highlighting the fact that women typically receive perfusion therapy less frequently and less rapidly than men. In addition, the report stressed that reperfusion patients should be monitored for a minimum of 24 hours. It also said that “Coordination between EMS and hospitals with common written protocols is at the center of STEMI management.” Other indications focused on ambulation, anticoagulant therapy and the importance of reducing the gap between optimal guideline protocols and actual care.